The research activities in Plant Pathology were started in 1920-21 in Section of Plant Pathologist to Government, U.P. with a Plant Pathologist and three research assistants and undergraduate and postgraduate teaching including Ph.D. (by research) of Plant Pathology under Professor Botany in Botany department of Government Agricultural College in 1920 and 1945, respectively with staff of two Assistant Professors (Class II, Gazetted Officer), one Lecturer and one Demonstrator. The post-graduate teaching including Ph.D. by research was started for the first time in the country in 1945-46. During III Five year plan in 1961 the Section of Plant Pathologist was strengthened with creation of the post of Systematic Mycologist, Plant Pathologist, Bacteriologist and Virologist (UPAS Jr. Scale Sec. C, class II Gazetted Officers) along with eight posts of Senior Research Assistant (Subordinate Agricultural Services-Group I), four posts of Junior Research Assistant (SAS Gr. II) and three posts of Subordinate Agricultural Service Group III, one post of Artist and one post of Statistical Assistant (each of SAS Gr. I) and with the appointment of Professor (Plant Pathology Plant Pathology section of the Botany department was elevated to a status of a separate Department of Plant Pathology.

In 1969 the newly created Department of Plant Pathology of Government Agricultural College and the Section of Plant Pathologist to Govt. U.P. were integrated under Professor & Head, Department of Plant Pathology in newly upgraded U.P. Institute of Agricultural Sciences with the creation of two posts of Class I (UPAS Sr. scale– Gazetted Officer) as Plant Bacteriologist and Plant Virologist, three posts of Class II (UPAS Jr. Scale, Gazetted Officer) as Assistant Plant Pathologist (Seed Pathologist), Assistant Plant Pathologist (Nematology) and Extension Pathologist during IV Five year plan. Later on, in 1975, U.P. Institute of Agricultural Sciences was further elevated to the status of the present Chandra Shekhar Azad University of Agriculture & Technology and the Department of Plant Pathology became a constituent of College of Agriculture of the University.

The first Plant Pathologist in the Section of Plant Pathologist to Government Uttar Pradesh was Dr. P. K. Dey (1920 -1945) and subsequent Plant Pathologists were Dr. U. B. Singh (1946-1949), Dr. A. K. Mitra (March 1949-October 1949), Dr. P. R. Mehta (1949-1952), Dr. Babu Singh (1952-1953), Dr. R. S. Mathur (1953-1966; 1968-March 1969) and Dr. I. N. Tandon (1966-1968). Since the creation of separate department, the Professor & Heads were Dr. H. K. Saksena (July, 1961- Dec. 20, 1982), Dr. I. N. Tandon (Dec. 21, 1982-June 30, 1985), Dr. Jagdish Swarup (July 1, 1985- Sept. 12, 1996), Dr. D.V. Singh (Sept 13, 1996- Sept 9, 1999), Dr. R.P. Dwivedi (Sept 10, 1999-July 14,2000), Dr. H. P. Shukla (July 15, 2000-July 17, 2003) and Dr. Kumud Kumar (July 18, 2003- continuing).